Anti -CD177 Rabbit pAb

價格：在線咨詢

貨號：

DRF101848

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	CD177 rabbit polyclonal
Protein full name	CD177 antigen
Synonyms	CD177, HNA-2a, HNA2A, NB1, NB1 GP, PRV-1, PRV1, CD177 molecule
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse CD177
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane
Uniprot ID	Q8R2S8

Applications

applications	species	dilution	Positive tissue
IHC	Mouse, Rat	1: 500-1: 2000	spleen, thymus gland
IF	Mouse, Rat	1: 500-1: 1000	spleen, thymus gland

Background

This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.

Images

	Immunohistochemistry analysis of paraffin-embedded rat spleen using CD177(GB11316) at dilution of 1:900
	Immunohistochemistry analysis of paraffin-embedded rat thymus gland using CD177(GB11316) at dilution of 1:900
	Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD177(GB11316) at dilution of 1:900

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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