Anti -CD105 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

DRF101850

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬(wàn)物

購(gòu)買數(shù)量：

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產(chǎn)品詳情操作說(shuō)明注意事項(xiàng)

Product Information

Description	CD105 rabbit polyclonal
Protein full name	Endoglin
Synonyms	Cell surface MJ7/18 antigen, CD105, Eng, Edg, FLJ41744, HHT1, ORW, ORW1
Immunogen	KLH conjugated Synthetic peptide corresponding to Human CD105
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane
Uniprot ID	P17813

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Human	1: 500-1: 1000	colon carcinoma, liver cancer,
IF	Human	1: 500-1: 1000	liver cancer, ovarian cancer

Background

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis.

Images

	Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using CD105 (GB113377) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded human liver cancer using CD105 (GB113377) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded human ovarian cancer using CD105 (GB113377) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed humanliver cancer using CD105 (GB113377) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed human ovarian cancer using CD105 (GB113377) at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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