Anti -CD163 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

DRF101855

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	CD163 rabbit polyclonal
Protein full name	Scavenger receptor cysteine-rich type 1 protein M130
Synonyms	CD163, M130, MM130, SCARI1, CD163 molecule
Immunogen	Recombinant protein corresponding to Mouse CD163
Isotype	IgG
Purity	Affinity purification
Subcellular location	Secreted,Cell membran
Uniprot ID	Q2VLH6

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Mouse, Rat	1:200-1:1000	spleen
IF	Mouse, Rat	1:200-1:1000	spleen

Background

Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 (By similarity).

Images

Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD163 (GB11340-1) at dilution of 1:300

Immunohistochemistry analysis of paraffin-embedded mouse Inflammatory spleen using CD163 (GB11340-1) at dilution of 1:500

Immunohistochemistry analysis of paraffin-embedded rat Inflammatory spleen using CD163 (GB11340-1) at dilution of 1:300

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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