Anti -CD105 Rabbit pAb

價格：在線咨詢

貨號：

DRF101857

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	CD105 rabbit polyclonal
Protein full name	Endoglin
Synonyms	CD105, END, ENG, HHT1, ORW, ORW1, Cell surface MJ7/18 antigen
Immunogen	KLH conjugated Synthetic peptide corresponding to mouse CD105
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane
Predicted MW.	70 kDa
Observed MW.	95 kDa
Uniprot ID	Q63961

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse	1: 500-1: 1000	kidney, thymus, liver, spleen
IHC	Mouse	1: 500-1: 1000	embryo, kindey, liver

Background

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis.

Images

	Western blot analysis of CD105 (GB113503) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse embryo using CD105 (GB113503) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse kindey using CD105 (GB113503) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse liver using CD105 (GB113503) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse subcutaneous transplanted tumor model of lewis cell using CD105 (GB113503) at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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