Anti -CD27 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

DRF101872

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	CD27 rabbit polyclonal
Protein full name	CD27 antigen
Synonyms	CD27, S152, S152, LPFS2, T14, TNFRSF7, Tp55, CD27 molecule
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse CD27
Isotype	IgG
Purity	Affinity purification
Subcellular location	Membrane
Uniprot ID	P26842, P41272

Applications

applications	species	dilution	positive tissue
IHC	Human, Rat	1: 500-1: 3500	tonsil
IF	Human, Rat	1: 1000-1: 2000	Immune spleen, lymph, thymus

Background

CD27 is a member of the tumor necrosis factor receptor superfamily. It is currently of interest to immunologists as a co-stimulatory immune checkpoint molecule. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Images

	Immunohistochemistry analysis of paraffin-embedded human tonsil using CD27 (GB11583) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed rat Immune spleen using CD27 (GB11583) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed rat lymph using CD27 (GB11583) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed rat thymus using CD27 (GB11583) at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles
Storage Buffer	PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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