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Product Information
Description |
CD62L rabbit polyclonal |
Protein full name |
L-selectin |
Synonyms |
SELL, CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1, selectin L |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CD62L |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
42 kDa |
Observed MW. |
42 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 1000-1: 2000 |
spleen, splenitis, thymus |
Background
L-selectin, also known as CD62L, is a cell adhesion molecule found on lymphocytes and the preimplantation embryo. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. CD62L contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. CD62L is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites.
Images
Western blot analysis of CD62L (GB11632) at dilution of 1: 1000 Lane 1: A549 cell lysate Lane 2: Jurkat cell lysate Lane 3: HepG2 cell lysate Lane 4: Mouse spleen tissue lysate Lane 5: Mouse splenitis tissue lysate Lane 6: Mouse thymus tissue lysate Lane 7: Rat spleen tissue lysate
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Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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