Anti -CD22 Rabbit pAb

價(jià)格：在線咨詢

貨號：

DRF101878

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	CD22 rabbit polyclonal
Protein full name	B-cell receptor CD22
Synonyms	CD22, SIGLEC-2, SIGLEC2, CD22 molecule
Immunogen	KLH conjugated Synthetic peptide corresponding to Human CD22
Isotype	IgG
Purity	Affinity purification
Predicted MW.	97 kDa
Observed MW.	125 kDa
Uniprot ID	P35329

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human	1: 500-1: 1000	Jurkat, Hek293, MCF7

Background

CD22 is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the over-activation of the immune system and the development of autoimmune diseases. CD22 is a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. The presence of Ig domains makes CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice.

Images

Western blot analysis of CD22

(GB11869) at dilution of 1: 1000

Lane 1: Jurkat cell lysate

Lane 2: Hek293 cell lysate

Lane 3: MCF7 cell lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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