服務(wù)熱線
400-1016-218
全國(guó)統(tǒng)一服務(wù)熱線
400-1016-218
科研好幫手 專業(yè)生產(chǎn)商
本公司產(chǎn)品僅供科研使用
您現(xiàn)在所在位置:主頁(yè) > 產(chǎn)品中心 > 抗體 >>一抗 >>白細(xì)胞抗原 >> Anti -CD146 Rabbit pAb
Product Information
Description |
CD146 rabbit polyclonal |
Protein full name |
Cell surface glycoprotein MUC18 |
Synonyms |
Gicerin, Melanoma cell adhesion molecule, Melanoma-associated antigen MUC18, CD146, Muc18, Mcam, MelCAM, Sendo1 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CD146 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
72 kDa |
Observed MW. |
120 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
blood vessels, uterus, stomach |
Background
MCAM is an immunoglobulin super family member originally described as a cell surface adhesion protein and marker of the progression and metastasis of melanoma . Expression of MCAM protein is seen in vascular endothelial cells, activated T lymphocytes, smooth muscle, and bone marrow stromal cells. Research studies demonstrate increased MCAM expression in endothelial cells from angiogenesis-related disorders, including inflammatorybowel disease, Crohn’s disease, rheumatoid arthritis, tumors, and chronic renal failure. MCAM-expressing human mesenchymal stromal cells in the hematopoietic microenvironment are responsible for maintaining the self-renewal of hematopoietic stem and progenitor cells through direct contact between hMSC and those cells .
Images
Western blot analysis of CD146 (GB11955) at dilution of 1: 1000 Lane 1: HMVEC cell lysate Lane 2: HUVEC cell lysate Lane 3: A375 cell lysate Lane 4: Mouse blood vessels tissue lysate Lane 5: Mouse uterus tissue lysate Lane 6: Mouse stomach tissue lysate Lane 7: Rat blood vessels tissue lysate Lane 8: Rat uterus tissue lysate Lane 9: Rat stomach tissue lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
合肥萬(wàn)物生物科技有限公司
客服熱線:400-1016-218
QQ:355185756
地址:安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室