Anti -CD105 Mouse mAb

價格：在線咨詢

貨號：

DRF101881

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	CD105 mouse monoclonal
Protein full name	Endoglin
Synonyms	Cell surface MJ7/18 antigen, CD105, Eng, Edg, FLJ41744, HHT1, ORW, ORW1
Immunogen	Recombinant protein corresponding to Mouse CD105
Isotype	IgG
Purity	Affinity purification
Predicted MW.	70 kDa
Observed MW.	95 kDa
Uniprot ID	Q63961

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse	1: 500-1: 1000	kidney, liver, lung

Background

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis.

Images

圖片 1.png

Western blot analysis of CD105 (GB12020)

at dilution of 1: 1000

Lane 1: Mouse kidney tissue lysate

Lane 2: Mouse liver tissue lysate

Lane 3: Mouse lung tissue lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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