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Anti -CD74 Mouse mAb

價格: 在線咨詢
貨號:
DRF101885
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

CD74 mouse monoclonal

Protein full name

HLA class II histocompatibility antigen gamma chain

Synonyms

CD74, DHLAG, HLADG, Ia GAMMA, Ii, p33, CLIP, HLA-DR antigens-associated invariant chain, Ia antigen-associated invariant chain

Immunogen

Recombinant human CD74 protein expressed in HEK293 cells

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membraneEndosome, Lysosome, Golgi apparatus,  Endoplasmic reticulum

Predicted MW.

34 kDa

Observed MW.

34 kDa

Uniprot ID

P04233




Applications


Applications

Species

Dilution

Positive Sample

WB

Human

1: 500-1: 1000

Raji

IHC/IF

Human

1: 500-1: 1000

hodgkin lymphoma, tonsil, gastric carcinoma, lung adenocarcinoma, gastric adenocarcinoma, tonsil




Background


CD74, also known as the MHC class II associated invariant chain (Ii), is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is produced in molar excess over MHC class II and some of this is expressed by an unknown pathway on the cell surface independent of or in association with MHC class II molecules. 




Images


Western blot analysis of CD74 

at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded human thodgkin lymphoma using CD74  at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded human tonsil using 

CD74 at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded human gastric carcinoma using CD74  at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed human lung adenocarcinoma using CD74  at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed human gastric adenocarcinoma using CD74 at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed human tonsil using 

CD74 at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.

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