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Product Information
Description |
Dynamin 1 rabbit polyclonal |
Protein full name |
Dynamin-1 |
Synonyms |
DNM1, DNM 1, Dynamin-1, DNM, EIEE31, Dynamin1, Dynamin 1, Dynamin |
Immunogen |
Recombinant protein corresponding to Mouse Dynamin 1 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cytoskeleton |
Predicted MW. |
98 kDa |
Observed MW. |
98 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 1000-1: 2000 |
brain, cerebral cortex, cerebellum |
IHC |
Mouse, Rat |
1: 300-1: 1000 |
brain |
IF |
Mouse, Rat |
1: 150-1: 300 |
brain |
Background
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15.
Images
Western blot analysis of Dynamin 1 (GB11855) at dilution of 1: 1000 Lane 1: Human brain tissue lysate Lane 2: Mouse brain tissue lysate Lane 3: Mouse cerebral cortex tissue lysate Lane 4: Mouse cerebellum tissue lysate Lane 5: Rat brain tissue lysate Lane 6: Rat cerebral cortex tissue lysate Lane 7: Rat cerebellum tissue lysate |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using Dynamin 1 (GB11855) at dilution of 1: 500
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Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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