Anti -SIRP alpha Rabbit pAb

價格：在線咨詢

貨號：

KT011555

產(chǎn)品規(guī)格：

100 μL

Applications：

WB | IHC | IF

Species：

M,R/M,R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	SIRP alpha rabbit polyclonal antibody
Protein full name	Tyrosine-protein phosphatase non-receptor type substrate 1
Synonyms	Sirpa, SIRPA, BIT, CD172A, MFR, MYD-1, P84, PTPNS1, SHPS1, SIRP, SIRPα, Signal-regulatory protein alpha, Signal regulatory protein alpha
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse SIRPα
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane
Predicted MW.	56 kDa
Observed MW.	100 kDa
Uniprot ID	P97797, P97710

Applications

Applications	Species	Dilution	Positive Sample
WB	Mouse, Rat	1: 500-1: 1000	brain, cerebellum, cerebral cortex
IHC/IF	Mouse, Rat	1: 500-1: 3600	kidney, lung, spleen

Background

Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation.

Images

	Western blot analysis of SIRPA (GB11914) at dilution of 1: 500
	Immunohistochemistry of paraffin embedded mouse kidney using SIRPA (GB11914) at dilution of 1: 3600 (250x lens)
	Immunohistochemistry of paraffin embedded rat lung using SIRPA (GB11914) at dilution of 1: 3600 (250x lens)
	Immunofluorescence of paraffin embedded mouse lung using SIRPA (GB11914) at dilution of 1: 1000 (300x lens)
	Immunofluorescence of paraffin embedded rat spleen using SIRPA (GB11914) at dilution of 1: 1000 (300x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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