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Product Information
Gene Name | MBP |
Protein Name | Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein) |
Human Gene Id | 4155 |
Human Swiss Prot No | P02686 |
Immunogen | Synthesized peptide derived from human Myelin Basic Protein(MBP) |
Specificity | This antibody detects endogenous levels of human Myelin Basic Protein(MBP) |
Source | Mouse/IgG1, Kappa |
Concentration | 1 mg/ml |
Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Applications
Applications | Species | Dilution |
|
IHC、IF | Human | 1:200-1:500 |
|
Background
myelin basic protein(MBP) Homo sapiens The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that
Images
Immunohistochemical analysis of paraffin-embedded Brain. 1, Antibody was diluted at 1:200(4°,overnight). 2, TRIS-EDTA of pH8.0 was used for antigen retrieval. |
|
Immunohistochemical analysis of paraffin-embedded Brain. 1, Antibody was diluted at 1:200(4°,overnight). 2, TRIS-EDTA of pH8.0 was used for antigen retrieval. |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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