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Product Information
Description |
PSD95 rabbit polyclonal |
Protein full name |
Disks large homolog 4 |
Synonyms |
DLG4, PSD95, SAP-90, SAP90, Dlgh4, PSD-95, SAP90A, discs large homolog 4, discs large MAGUK scaffold protein 4 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse PSD95 |
Isotype |
IgG |
Predicted MW. |
95 kDa |
Observed MW. |
95 kDa |
Purity |
Affinity purification |
Subcellular location |
|
Uniprot ID |
Applications
applications |
species |
dilution |
Positive tissue |
WB |
Mouse, Rat |
1: 500-1: 1000 |
brain |
IHC |
Mouse, Rat |
1: 100-1: 200 |
brain |
IF |
Mouse, Rat |
1: 100-1: 200 |
brain, cerebellum |
Background
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.
Images
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Western blot analysis of PSD95 (GB11277) at dilution of 1:750. Line 1: mouse brain tissue lysate Line 2:rat cerebral infarction tissue lysate Line 3:rat brain tissue lysate
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Immunohistochemistry analysis of paraffin-embedded mouse brain using PSD95 (GB11277) at dilution of 1: 200
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Immunohistochemistry analysis of paraffin-embedded rat brain using PSD95 (GB11277) at dilution of 1: 200
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Immunofluorescent analysis of paraformaldehyde-fixed mouse cerebellum using PSD95 (GB11277) at dilution of 1: 200 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using PSD95 (GB11277) at dilution of 1: 200 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat brain using PSD95 (GB11277) at dilution of 1: 200 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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