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Product Information
Description |
FMRP rabbit polyclonal |
Protein full name |
Synaptic functional regulator FMR1 |
Synonyms |
Fragile X mental retardation protein 1 homolog, FMRP, Protein FMR-1, mFmr1p, Fmr1, Fmr-1, FRAXA, POF, POF1 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse FMRP |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Mouse, Rat |
1: 600-1: 1200 |
prefrontal lobe, cerebellum |
Background
The selective RNA-binding protein FMRP forms a messenger ribonucleoprotein complex that associates with polyribosomes, implicating in regulation of translation. FMR1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to and reperss the mRNA. It also has a role in the transport of mRNA from the nucleus to the cytoplasm. FMR1 exists several isforms and the molecular weight of FMR1 is about 59-72 kDa.
Images
|
Immunohistochemistry analysis of paraffin-embedded mouse prefrontal lobe using FMRP (GB113089) at dilution of 1: 1200 |
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Immunohistochemistry analysis of paraffin-embedded rat cerebellum using FMRP (GB113089) at dilution of 1: 1200 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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