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Anti -Doublecortin Rabbit pAbVV

價格: 在線咨詢
貨號:
KT011663
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
M/R
購買數(shù)量:
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Product Information


Description

Doublecortin rabbit polyclonal antibody

Protein full name

Neuronal migration protein doublecortin

Synonyms

DCX, DBCN, DC, LISX, SCLH, XLIS, doublecortin

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Doublecortin

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Cell projection

Uniprot ID

O88809, Q9ESI7



Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Mouse, Rat

1: 1000-1: 2000

brain

    



Background


Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.




Images



Immunohistochemistry of paraffin embedded mouse brain using Doublecortin (GB11317) at dilution of 1:1000 (200x lens)

Immunohistochemistry of paraffin embedded rat brain using Doublecortin (GB11317) at dilution of 1:1000 (200x lens)

Immunofluorescence of paraffin embedded mouse brain using Doublecortin (GB11317) at dilution of 1:1000 (200x lens)


Immunofluorescence of paraffin embedded rat brain using Doublecortin (GB11317) at dilution of 1:1000 (200x lens)





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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