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Product Information
Description |
Doublecortin rabbit polyclonal antibody |
Protein full name |
Neuronal migration protein doublecortin |
Synonyms |
DCX, DBCN, DC, LISX, SCLH, XLIS, doublecortin |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Doublecortin |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cytoplasm, Cell projection |
Uniprot ID |
O88809, Q9ESI7 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Mouse, Rat |
1: 1000-1: 2000 |
brain |
Background
Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.
Images
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Immunohistochemistry of paraffin embedded mouse brain using Doublecortin (GB11317) at dilution of 1:1000 (200x lens) |
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Immunohistochemistry of paraffin embedded rat brain using Doublecortin (GB11317) at dilution of 1:1000 (200x lens) |
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Immunofluorescence of paraffin embedded mouse brain using Doublecortin (GB11317) at dilution of 1:1000 (200x lens)
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Immunofluorescence of paraffin embedded rat brain using Doublecortin (GB11317) at dilution of 1:1000 (200x lens)
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Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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