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Product Information
Description |
Synaptojanin rabbit polyclonal |
Protein full name |
Synaptojanin-1 |
Synonyms |
INPP5G, KIAA0910, SYNJ1, Polyphosphoinositide phosphatase, PARK20, KIAA0910, 5-trisphosphate 5-phosphatase 1 |
Immunogen |
Recombinant protein corresponding to Mouse Synaptojanin |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
173 kDa |
Observed MW. |
173 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse |
1: 300-1: 800 |
brain, stomach |
Background
Synaptojanin 1, a polyphosphoinositide phosphatase, is expressed as two major alternatively spliced isoforms of 145 kDa (SJ145) and 170 kDa (SJ170), which are thought to have pleiotropic roles in endocytosis, signaling and actin function. SJ145 is highly enriched in nerve terminals where it participates in clathrin-dependent synaptic vesicle recycling. SJ170, which differs from SJ145 by the presence of a carboxy-terminal extension, is the predominant isoform in developing neurons and is expressed in a variety of tissues.
Images
Western blot analysis of SYNJ1 (GB113172) at dilution of 1: 800 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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