Anti -Cyclin A2 Rabbit pAb

價格：在線咨詢

貨號：

KT011705

產品規(guī)格：

100 μL

Applications：

WB | IHC | IF

Species：

H,M/H,M,R/H,M,R/

品牌：

萬物

購買數量：

立即詢價在線咨詢 400-1016-218

產品詳情操作說明注意事項

Product Information

Description	Cyclin A2 rabbit polyclonal
Protein full name	Cyclin-A2
Synonyms	Cyclin-A, Cyclin A, CCNA2, CCN1, CCNA
Immunogen	Recombinant protein corresponding to Human Cyclin A2
Isotype	IgG
Purity	Affinity purification
Subcellular location	Nucleus, Cytoplasm
Predicted MW.	49 kDa
Observed MW.	55 kDa
Uniprot ID	P20248, P51943, G3V802

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse	1: 500-1: 1000	lymph nodes, spleen
IHC	Human, Mouse, Rat	1: 600-1: 1200	lymph nodes, brain, testis
IF	Human, Mouse, Rat	1: 250-1: 1000	lung cancer, kidney

Background

Cyclin A2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. Cyclin A2 binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. Cyclin A2 could be phosphorylated during the G2/M.

Images

	Western blot analysis of Cyclin A2 (GB111132) at dilution of 1: 1000 Lane 1: HCT116 cell lysate Lane 2: Jurkat cell lysate Lane 3: HT29 cell lysate Lane 4: K562 cell lysate Lane 5: SW480 cell lysate Lane 6: Mouse lymph nodes tissue lysate Lane 7: Mouse spleen tissue lysate
	Immunohistochemistry analysis of paraffin-embedded using human lymph nodes Cyclin A2 (GB111132) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded using mouse brain Cyclin A2 (GB111132) at dilution of 1: 600
	Immunohistochemistry analysis of paraffin-embedded using rat testis Cyclin A2 (GB111132) at dilution of 1: 600
	Immunofluorescent analysis of paraffin-embedded using human lung cancer Cyclin A2 (GB111132) at dilution of 1: 500
	Immunofluorescent analysis of paraffin-embedded using mouse kidney Cyclin A2 (GB111132) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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