Mpz, Myelin protein P0, CHM, CMT1, CMT1B, CMT2I, CMT2J, CMT4E, CMTDI3, CMTDID, DSS, HMSNIB, MPP, P0, Myelin protein zero, CHN2
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Myelin Protein Zero
Isotype
IgG
Purity
Affinity purification
Predicted MW.
28 kDa
Observed MW.
28 kDa
Uniprot ID
P27573, P06907
Applications
Applications
Species
Dilution
Positive Tissue
WB
Mouse, Rat
1: 500-1: 1000
optic nerve,
spinal cord
Background
Myelin protein zero (P0, MPZ) is a single membrane glycoprotein encoded by the MPZ gene. P0 is a major structural component of the myelin sheath in the peripheral nervous system (PNS). Myelin protein zero is expressed by Schwann cells and accounts for over 50% of all proteins in the peripheral nervous system, making it the most common protein expressed in the PNS. Mutations in myelin protein zero can cause myelin deficiency and are associated with neuropathies like Charcot–Marie–Tooth disease and Dejerine–Sottas disease.
Images
Western blot analysis of Myelin Protein Zero (GB11747) at dilution of 1: 1000
Lane 1: Mouse optic nerve tissue lysate
Lane 2: Mouse spinal cord tissue lysate
Lane 3: Mouse hypophysis tissue lysate
Lane 4: Rat optic nerve tissue lysate
Lane 5: Rat spinal cord tissue lysate
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .