Anti -14-3-3 Tau Rabbit pAb

價格：在線咨詢

貨號：

KT011728

產品規(guī)格：

100 μL

Applications：

Species：

H,M,R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產品詳情操作說明注意事項

Product Information

Description	14-3-3 Tau rabbit polyclonal antibody
Protein full name	14-3-3 protein theta
Synonyms	14-3-3 protein tau, Ywhaq
Immunogen	Recombinant protein corresponding to Mouse 14-3-3 Tau
Isotype	IgG
Purity	Affinity purification
Predicted MW.	28 kDa
Observed MW.	28 kDa
Uniprot ID	P27348, P68254, P68255

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	brain, lung, thymus

Background

The 14-3-3 family of proteins are important regulatory molecules ubiquitiously expressed in all eukarryotic cells which bind to numerous signaling proteins in various pathways driving critical cellular pathways of apoptosis, differentiation and cell cycle. 14-3-3 theta specifically has also been shown to play an important regulatory role in the TLR2 signaling pathways as a negative regulator of TLR2 ligand Pam3CySk4 induced NF-kB activation. 14-3-3 theta has previously been shown to interact with TLR4 ligand and MyD88 dependent phosphorylated PkC epsilon. 14-3-3 theta in the TLR4 signaling pathway is a positive regulator controlling release of IRF3 indcuded pro-inflammatory cytokines RANTES and IP-10.

Images

Picture 1.png

Western blot analysis of 14-3-3 τ (GB111166) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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