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Anti -S6K1 Rabbit pAb

價格: 在線咨詢
貨號:
KT011731
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC
Species:
H
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

S6K1 rabbit polyclonal antibody

Protein full name

Ribosomal protein S6 kinase beta-1

Synonyms

S6K-beta-1, S6K1, P70S6K1, S6K, Ribosomal protein S6 kinase I, P70 S6 kinase alpha, Rps6kb1, 70 kDa ribosomal protein S6 kinase 1

Immunogen

Recombinant protein corresponding to Human S6K1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm

Uniprot ID

P23443, Q8BSK8, P67999




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human

1: 600-1: 2000

liver, liver cancer, lung cancer




Background


This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex.




Images


Picture 1.png

Immunohistochemistry of paraffin embedded human liver using P70S6K1 (GB111181) at dilution of 1:1200 (400x lens)

Picture 2.png

Immunohistochemistry of paraffin embedded human liver cancer using P70S6K1 (GB111181) at dilution of 1:1200 (400x lens)

Picture 3.png

Immunohistochemistry of paraffin embedded human lung cancer using P70S6K1 (GB111181) at dilution of 1:1200 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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