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Anti -Prohibitin Rabbit pAb

價格: 在線咨詢
貨號:
KT011772
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
M,R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

Prohibitin rabbit polyclonal antibody

Protein full name

Prohibitin

Synonyms

B-cell receptor-associated protein 32, C-BAP 32, Phb, PHB, HEL-215, HEL-S-54e, PHB1, Prohibitin

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Prohibitin

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm

Uniprot ID

P67778, P67779




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Mouse, Rat

1: 700-1: 1400

brain, heart, small intestine




Background


Prohibitin, also known as PHB, a member of the Band-7 family of proteins, is widely distributed in bacteria, plants, yeast, protozoa and mammals and is important in cell proliferation, differentiation and apoptosis . This protein localizes to the inner membrane of mitochondria, where it acts as a chaperone protein, and is also found in the nucleus, where it negatively regulates transcription. Recent study confirmed that the expression and distribution of PHB, which is a nuclear matrix protein, affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis .




Images


Immunohistochemistry of paraffin embedded mouse brain using Prohibitin (GB111326) at dilution of 1:700 (400x lens)

Immunohistochemistry of paraffin embedded mouse heart using Prohibitin (GB111326) at dilution of 1:700 (400x lens)

Immunohistochemistry of paraffin embedded mouse small intestine using Prohibitin (GB111326) at dilution of 1:700 (400x lens)

Immunohistochemistry of paraffin embedded rat brain using Prohibitin (GB111326) at dilution of 1:700 (400x lens)

Immunohistochemistry of paraffin embedded rat heart using Prohibitin (GB111326) at dilution of 1:700 (400x lens)

Immunohistochemistry of paraffin embedded rat small intestine using Prohibitin (GB111326) at dilution of 1:700 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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