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Product Information
Description |
Prohibitin rabbit polyclonal antibody |
Protein full name |
Prohibitin |
Synonyms |
B-cell receptor-associated protein 32, C-BAP 32, Phb, PHB, HEL-215, HEL-S-54e, PHB1, Prohibitin |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Prohibitin |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Nucleus, Cytoplasm |
Uniprot ID |
P67778, P67779 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Mouse, Rat |
1: 700-1: 1400 |
brain, heart, small intestine |
Background
Prohibitin, also known as PHB, a member of the Band-7 family of proteins, is widely distributed in bacteria, plants, yeast, protozoa and mammals and is important in cell proliferation, differentiation and apoptosis . This protein localizes to the inner membrane of mitochondria, where it acts as a chaperone protein, and is also found in the nucleus, where it negatively regulates transcription. Recent study confirmed that the expression and distribution of PHB, which is a nuclear matrix protein, affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis .
Images
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Immunohistochemistry of paraffin embedded mouse brain using Prohibitin (GB111326) at dilution of 1:700 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse heart using Prohibitin (GB111326) at dilution of 1:700 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse small intestine using Prohibitin (GB111326) at dilution of 1:700 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using Prohibitin (GB111326) at dilution of 1:700 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat heart using Prohibitin (GB111326) at dilution of 1:700 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat small intestine using Prohibitin (GB111326) at dilution of 1:700 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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