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Anti -TTK/Mps1 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011777
產(chǎn)品規(guī)格:
100 μL
Applications:
WB | IHC
Species:
H,H
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information

Description

TTK rabbit polyclonal

Protein full name

Dual specificity protein kinase TTK

Synonyms

Phosphotyrosine picked threonine-protein kinase, PYT, TTK, MPS1, MPS1L1

Immunogen

KLH conjugated Synthetic peptide corresponding to Human TTK

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Predicted MW.

97 kDa

Observed MW.

97 kDa

Uniprot ID

P33981





Applications

Applications

Species

Dilution

Positive Tissue

WB

Human

1: 500-1: 1000

HeLa, MCF7, K562, Jurkat

IHC

Human

1: 750-1: 1500

colon cancer, esophageal cancer





Background

Mps1 family of kinases colocalizes with mitotic checkpoint proteins in kinetochores and/or spindle pole bodies/centrosomes. TTK has been shown to be a cell cycle-regulated kinase displaying maximum activity during M phase. Its kinase activity is required for proper chromosome segregation during mitosis through its involvements in microtubule-chromosome attachment error correction and the mitotic checkpoint.





Images

Western blot analysis of TTK (GB111371)
at dilution of 1: 1000
Lane 1: Hela cell lysate
Lane 2: MCF7 cell lysate
Lane 3: K562 cell lysate
Lane 4: Jurkat cell lysate

Immunohistochemistry analysis of paraffin-embedded human colon cancer using TTK (GB111371) at dilution of 1: 750

Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using TTK (GB111371) at dilution of 1: 750





Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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