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Product Information
Description |
Cdk9 rabbit polyclonal |
Protein full name |
Cyclin-dependent kinase 9 |
Synonyms |
Cell division protein kinase 9, Cdk9, C2k, CDC2L4, CTK1, PITALRE, TAK |
Immunogen |
Recombinant protein corresponding to Mouse Cdk9 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IF |
Rat |
1: 500-1: 1000 |
brain |
Background
CDK9 (cyclin-dependent kinase 9) is a member of the cyclin-dependent protein kinase family. It is involved in the regulation of transcription. CDK9 is a member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex. It regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors. CDK9 promotes RNA synthesis in genetic programs for cell growth, differentiation and viral pathogenesis. The CDK9/cyclin-K complex also has kinase activity towards CTD of RNAPII and can substitute for CDK9/cyclin-T P-TEFb in vitro. Chronic activation of CDK9 causes cardic myocyte enlargement leading to cardiac hypertrophy and confers a predisposition to heart failure.
Images
Immunohistochemistry analysis of paraffin-embedded rat brain using Cdk9 (GB111389) at dilution of 1: 600 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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