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Product Information
Description |
CRIF1 rabbit polyclonal antibody |
Protein full name |
Growth arrest and DNA damage-inducible proteins-interacting protein 1 |
Synonyms |
39S ribosomal protein L59, mitochondrial, MRP-L59, Gadd45gip1, CKbetaBP2, CKII beta binding protein 2, G45IP_HUMAN, p53 responsive gene 6, L2-interacting nuclear protein 1, Papillomavirus |
Immunogen |
Recombinant protein corresponding to Mouse CRIF1 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
26 kDa |
Observed MW. |
25 kDa |
Uniprot ID |
Q9CR59, Q5XJW2 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Mouse, Rat |
1: 500-1: 1000 |
liver, spleen, lung |
Background
GADD45GIP1 acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
Images
Western blot analysis of GADD45GIP1 (GB111592) at dilution of 1: 500 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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