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Anti -UBE2E3 Rabbit pAb

價格: 在線咨詢
貨號:
KT011951
產(chǎn)品規(guī)格:
100ul
Applications:
WB
Species:
H/M/R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

UBE2E3 rabbit polyclonal antibody

Protein full name

Ubiquitin-conjugating enzyme E2 E3

Synonyms

E2 ubiquitin-conjugating enzyme E3, UbcM2, Ubiquitin carrier protein E3, Ubce4, Ubiquitin-conjugating enzyme E2-23 kDa, Ubiquitin-protein ligase E3, Ube2e3, UBCH9

Immunogen

Recombinant protein corresponding to Mouse UBE2E3

Isotype

IgG

Purity

Affinity purification

Predicted MW.

23 kDa

Observed MW.

23 kDa

Uniprot ID

Q969T4, P52483




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 1000-1: 1500

testis, brain, kidney




Background


The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases or E3s. UBE2E3 is a member of the E2 ubiquitin-conjugating enzyme family. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48', as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.




Images


Picture 1.png

Western blot analysis of Ube2e3 (GB111203) at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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