Anti -Skp1 Rabbit pAb

價格：在線咨詢

貨號：

KT011954

產(chǎn)品規(guī)格：

Applications：

IHC/IF

Species：

H/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	Skp1 rabbit polyclonal antibody
Protein full name	S-phase kinase-associated protein 1
Synonyms	Cyclin-A/CDK2-associated protein p19, S-phase kinase-associated protein 1A, p19A, p19skp1, Skp1, Skp1a
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse Skp1
Isotype	IgG
Purity	Affinity purification
Subcellular location	Nucleus, cytoplasm
Uniprot ID	Q6PEC4

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Human, Rat	1: 1500-1: 3000	colon, heart, liver, lung

Background

SKP1A is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin proteolysis through an F-box motif. SKP1A also collaborates with a network of proteins to control beta-catenin levels and affects the activity level of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor.

Images

	Immunohistochemistry of paraffin embedded rat heart using SKP1 (GB111230) at dilution of 1:1600 (400x lens)
	Immunohistochemistry of paraffin embedded rat lung using SKP1 (GB111230) at dilution of 1:1600 (400x lens)
	Immunofluorescence of paraffin embedded human colon using SKP1 (GB111230) at dilution of 1:1600 (400x lens)
	Immunofluorescence of paraffin embedded human liver using SKP1 (GB111230) at dilution of 1:1600 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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