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Anti -NFAT2 Rabbit pAb

價格: 在線咨詢
貨號:
KT012131
產(chǎn)品規(guī)格:
100ul
Applications:
IHC/IF
Species:
M/R,M/R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

NFAT2 rabbit polyclonal

Protein full name

Nuclear factor of activated T-cells, cytoplasmic 1

Synonyms

NF-ATc1, NFATc1, Nfat2, NFAT transcription complex cytosolic component, NFATc

Immunogen

Recombinant protein corresponding to

Mouse NFAT2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

O88942, D3ZE20




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 400-1: 1000

skin, lung

IF

Mouse, Rat

1: 250-1: 500

skin, lung




Background


The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.




Images


image.png

Immunohistochemistry analysis of paraffin-embedded mouse skin using NFAT2 (GB111027) at dilution of 1: 800

image.png

Immunohistochemistry analysis of paraffin-embedded rat skin using NFAT2 (GB111027) at dilution of 1: 800

image.png

Immunohistochemistry analysis of paraffin-embedded rat lung using NFAT2 (GB111027) at dilution of 1: 800




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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