Anti -KMT1B / SUV39H2 Rabbit pAb

價格：在線咨詢

貨號：

KT012137

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC/IF

Species：

H,M,R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	SUV39H2 rabbit polyclonal antibody
Protein full name	Histone-lysine N-methyltransferase SUV39H2
Synonyms	Histone H3-K9 methyltransferase 2, KMT1B, H3-K9-HMTase 2, Lysine N-methyltransferase 1B, Suppressor of variegation 3-9 homolog 2, Su(var)3-9 homolog 2, SUV39H2
Immunogen	Recombinant protein corresponding to Mouse SUV39H2
Isotype	IgG
Purity	Affinity purification
Subcellular location	Nucleus
Uniprot ID	Q9H5I1

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Human, Mouse, Rat	1: 500-1: 4000	breast cancer, hippocampus, testis

Background

Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats.

Images

	Immunohistochemistry of paraffin embedded human breast cancer using Suv39h2 (GB111054) at dilution of 1:2000 (400x lens)
	Immunofluorescence of paraffin embedded human breast cancer using Suv39h2 (GB111054) at dilution of 1:2000 (400x lens)
	Immunofluorescence of paraffin embedded mouse hippocampus using Suv39h2 (GB111054) at dilution of 1:2000 (400x lens)
	Immunofluorescence of paraffin embedded rat testis using Suv39h2 (GB111054) at dilution of 1:2000 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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