Anti -Dnmt3a Rabbit pAb

價格：在線咨詢

貨號：

KT012151

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC/IF

Species：

M,R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	Dnmt3a rabbit polyclonal antibody
Protein full name	DNA (cytosine-5)-methyltransferase 3A
Synonyms	Dnmt3a, DNA methyltransferase MmuIIIA, DNA MTase MmuIIIA, M.MmuIIIA, Dnmt3a
Immunogen	Recombinant protein corresponding to Mouse Dnmt3a
Isotype	IgG
Purity	Affinity purification
Subcellular location	Nucleus, Cytoplasm
Uniprot ID	O88508, Q1LZ53

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Mouse, Rat	1: 500-1: 3200	colon, embryonic mouse, embryonic rat, kidney, lymph node, placenta, spleen, testis

Background

Inactivation of tumor suppressor genes is a key component of the development of all common forms of human cancers. Aberrant methylation may contribute to many of the changes, both physiological and pathological, associated with aging, including tumor development. Hypermethylation of CpG island-containing promoters is associated with the inactivation of genes important to tumor angiogenesis and progression. DNA methytransferase (DNMT3a) is necessary for the maintenance of the methylation process.

Images

	Immunohistochemistry of paraffin embedded mouse embryonic mouse using Dnmt3a (GB111355) at dilution of 1:3200 (400x lens)
	Immunohistochemistry of paraffin embedded mouse placenta using Dnmt3a (GB111355) at dilution of 1:3200 (400x lens)
	Immunohistochemistry of paraffin embedded mouse spleen using Dnmt3a (GB111355) at dilution of 1:3200 (400x lens)
	Immunohistochemistry of paraffin embedded mouse testis using Dnmt3a (GB111355) at dilution of 1:3200 (400x lens)
	Immunohistochemistry of paraffin embedded rat colon using Dnmt3a (GB111355) at dilution of 1:3200 (400x lens)
	Immunohistochemistry of paraffin embedded rat placenta using Dnmt3a (GB111355) at dilution of 1:3200 (400x lens)
	Immunohistochemistry of paraffin embedded rat spleen using Dnmt3a (GB111355) at dilution of 1:3200 (400x lens)
	Immunofluorescence of paraffin embedded mouse kidney using Dnmt3a (GB111355) at dilution of 1:1600 (400x lens)
	Immunofluorescence of paraffin embedded mouse placenta using Dnmt3a (GB111355) at dilution of 1:1600 (400x lens)
	Immunofluorescence of paraffin embedded mouse testis using Dnmt3a (GB111355) at dilution of 1:1600 (400x lens)
	Immunofluorescence of paraffin embedded rat embryonic rat using Dnmt3a (GB111355) at dilution of 1:1600 (400x lens)
	Immunofluorescence of paraffin embedded rat lymph node using Dnmt3a (GB111355) at dilution of 1:1600 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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