Anti -VR1 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT012172

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

立即詢價(jià) 在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	VR1 rabbit polyclonal antibody
Protein full name	Transient receptor potential cation channel subfamily V member 1
Synonyms	TrpV1, Capsaicin receptor, Osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, VR1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse VR1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	95 kDa
Observed MW.	95 kDa
Uniprot ID	Q8NER1

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human	1: 500-1: 1000	Hacat, T-47D, PC12

Background

TRPV1 is a nonselective cation channel that resembles members of the transient receptor potential (TRP) family of ion channels. Receptor-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. May be involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects. Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accubens by affecting AMPA receptors endocytosis.

Images

Picture 1.png

Western blot analysis of TRPV1 (GB111088) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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