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Anti -CD35 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101927
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

CD35 rabbit polyclonal

Protein full name

Complement receptor type 1

Synonyms

C3b/C4b receptor, CD35, CR1, C3BR, C3 binding protein, C4BR , Knops blood group antigen

Immunogen

KLH conjugated Synthetic peptide

corresponding to Human CD35

Isotype

IgG

Purity

Affinity purification

Predicted MW.

224 kDa

Observed MW.

224 kDa




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

inflamed spleen, inflamed lung,

inflamed kidney


IF

Human, Rat 1:650-1:1300




Background


This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis.




Images


圖片 1.png

Western blot analysis of CD35

at dilution of 1: 1000

Lane 1: Mouse inflamed spleen tissue lysate

Lane 2: Mouse inflamed lung tissue lysate

Lane 3: Mouse inflamed kidney tissue lysate

Lane 4: Rat inflamed lung tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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