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Product Information
Description |
Factor B rabbit polyclonal |
Protein full name |
Complement factor B |
Synonyms |
C3/C5 convertase, Cfb, Bf, H2-Bf, AHUS4, Properdin factor B, Glycine-rich beta glycoprotein, Complement Factor B, BFD |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Factor B |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
85 kDa |
Observed MW. |
69/85 kDa |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, |
1: 500-1: 1000 |
liver |
Background
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Images
Western blot analysis of Factor B at dilution of 1: 1000 Lane 1: Mouse liver tissue lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.
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