KLH conjugated Synthetic phosphopeptide corresponding to Human ERK1 (T202/Y204) + ERK2 (T185/Y187)
Isotype
IgG
Purity
Affinity purification
Predicted MW.
41 kDa
Observed MW.
43 kDa
Uniprot ID
P63085, P63086
Applications
Applications
Species
Dilution
Positive Sample
WB
Mouse, Rat
1: 400-1: 800
lung, kidney
Background
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
Images
Western blot analysis of ERK1 (T202/Y204) + ERK2 (T185/Y187) at dilution of 1: 800
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100μg/ml BSA and 50% glycerol.