Anti -AKT1 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT012268

產(chǎn)品規(guī)格：

100ul

Applications：

Species：

H/M/R

品牌：

萬物

購買數(shù)量：

立即詢價(jià) 在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	AKT1 rabbit polyclonal antibody
Protein full name	RAC-alpha serine/threonine-protein kinase
Synonyms	AKT1 kinase, Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha, Akt1, Thymoma viral proto-oncogene, Akt
Immunogen	KLH conjugated Synthetic peptide corresponding to Rat AKT1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	56 kDa
Observed MW.	60 kDa
Uniprot ID	P31749, P31750, P47196

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1500	heart, brain

Background

The AKT1 protein plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4.This protein is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.

Images

Picture 1.png

Western blot analysis of AKT1 at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

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