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Anti -GSK3 beta Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT012274
產(chǎn)品規(guī)格:
100ul
Applications:
WB/IHC/IF
Species:
H/M/R,H/M/R,H/M/R
購(gòu)買(mǎi)數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

GSK3 beta rabbit polyclonal

Protein full name

Glycogen synthase kinase-3 beta

Synonyms

GSK3B, Gsk3b, 7330414F15Rik, 8430431H08Rik, C86142, GSK-3, GSK-3beta, GSK3, glycogen synthase kinase 3 beta

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse GSK3β 

Isotype

IgG

Predicted MW.

47 kDa

Observed MW.

47 kDa

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus, Cell membrane

Uniprot ID

P49841, Q9WV60, P18266



Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

lung

IHC

Human, Mouse, Rat

1: 500-1: 1000

testis, ovary cancer

IF

Human, Mouse, Rat

1: 200-1: 500

liver cancer



Background


Glycogen synthase kinase-3 (GSK-3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and an inactivating agent of glycogen synthase. Two isoforms, alpha (GSK3A) and beta, show a high degree of amino acid homology. GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.




Images


Western blot analysis of GSK3 beta (GB11099) at dilution of 1: 1000.

Lane 1: HeLa cell lysate

Lane 2: HepG2 cell lysate

Lane 3: C6 cell lysate

Lane 4: Mouse lung tissue lysate


Immunohistochemistry analysis of paraffin-embedded human ovary cancer GSK3 beta at dilution of 1: 600



Immunohistochemistry analysis of paraffin-embedded rat testis GSK3 beta at dilution of 1: 600



Immunofluorescence analysis of paraffin-embedded human liver cancer using GSK3 beta at dilution of 1: 300




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




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