Anti -Rab5 Rabbit pAb

價格：在線咨詢

貨號：

KT012276

產(chǎn)品規(guī)格：

100 μL

Applications：

WB/IHC/IF

Species：

H/M/R,H,H

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	Rab5 rabbit polyclonal antibody
Protein full name	Ras-related protein Rab-5A
Synonyms	Rab5a, NnyRab5a, Ubiquitin-protein ligase D3
Immunogen	KLH conjugated Synthetic peptide corresponding to Human Rab5
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm, Cell membrane
Predicted MW.	24 kDa
Observed MW.	24 kDa
Uniprot ID	P20339, Q9CQD1

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse, Rat	1: 500-1: 1000	brain, testis
IHC/IF	Human	1: 500-1: 2000	lung, lung cancer

Background

Rab5 is a 24 kDa GTP-binding protein that regulates the fusion of plasma membrane -derived clathrin-coated vesicles with early endosomes, and homotypic fusion among early endosomes1. Localized to the cytoplasmic side of the plasma membrane, clathrin -coated vesicles and early endosomes, Rab5 appears to regulate vesicle fusion through a cycle of GDP/GTP e xchange and GTP hydrolysis. The different guanine nucleotide binding states of Rab5 may affect its ability to associate or dissociate with membranes during endocytotic membrane traffic.

Images

	Western blot analysis of RAB5A (GB111104) at dilution of 1: 500
	Immunohistochemistry of paraffin embedded human lung cancer using RAB5A (GB111104) at dilution of 1: 1000 (400x lens)
	Immunohistochemistry of paraffin embedded human lung using RAB5A (GB111104) at dilution of 1: 1000 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

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