Anti -Rab11A Rabbit pAb

價格：在線咨詢

貨號：

KT012280

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

H/M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	Rab11A rabbit polyclonal antibody
Protein full name	Ras-related protein Rab-11A
Synonyms	Rab-11, Rab11a, Rab11
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse Rab11A
Isotype	IgG
Purity	Affinity purification
Predicted MW.	24 kDa
Observed MW.	24 kDa
Uniprot ID	P62491, P62492, P62494

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	brain, spleen

Background

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras super family of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. Rab11a and Rab11b are known markers for protein trafficking, sorting, and recycling in the endosomal pathway. The Rab11 proteins are enriched in recycling endosomes and the trans-Golgi network, where they regulate membrane recycling back to the plasma membrane.

Images

Picture 1.png

Western blot analysis of RAB11A at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

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