Anti -TNF Receptor II Rabbit pAb

價格：在線咨詢

貨號：

DRF101668

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	TNF Receptor II rabbit polyclonal
Protein full name	Tumor necrosis factor receptor superfamily member 1B
Synonyms	Tumor necrosis factor receptor 2, TNFR2, p75, Tumor necrosis factor receptor type II, TNFRII, p80 TNF-alpha receptor, CD120b, Etanercept, TBP-2, TBPII, TNFRSF1B, TNFBR
Immunogen	KLH conjugated Synthetic peptide corresponding to Human TNF Receptor II
Isotype	IgG
Purity	Affinity purification
Predicted MW.	48 kDa
Observed MW.	73 kDa
Uniprot ID	P20333

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human	1: 500-1: 1000	Jurkat, A549

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.

Images

Western blot analysis of TNF Receptor II (GB111013) at dilution of 1: 1000

Lane 1: Jurkat cell lysate

Lane 2: A549 cell lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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