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Product Information
Description |
IL-34 rabbit polyclonal |
Protein full name |
Interleukin-34 |
Synonyms |
IL-34, Chromosome 16 open reading frame 77 , C16orf77, FPT025 |
Immunogen |
Recombinant protein corresponding to Mouse IL-34 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Mouse, Rat |
1: 500-1: 1000 |
small intestine, heart |
Background
IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.
Images
|
Immunohistochemistry analysis of paraffin-embedded mouse small intestine using IL-34 (GB111855) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse heart using IL-34 (GB111855) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat heart using IL-34 (GB111855) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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