Anti -TNF Receptor II Rabbit pAb

價(jià)格：在線咨詢

貨號：

DRF101669

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	TNF Receptor II rabbit polyclonal
Protein full name	Tumor necrosis factor receptor superfamily member 1B
Synonyms	Tumor necrosis factor receptor 2, TNFR2, P75, Tumor necrosis factor receptor type II, TNFRII, P80 TNF-alpha receptor,CD120b, Etanercept, TBP-2, TBPII, TNFRSF1B, TNFBR
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse TNF Receptor II
Isotype	IgG
Purity	Affinity purification
Predicted MW.	48 kDa
Observed MW.	73 kDa
Uniprot ID	P20333, P25119, Q80WY6

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	brain, cerebral cortex, spleen, cerebellum, spinal cord

Background

The protein encoded by this gene is a member of the TNF-receptor super family. This protein and TNF-receptor 1 form a hetero complex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.

Images

Western blot analysis of TNF Receptor II

(GB111014) at dilution of 1: 1000

Lane 1: SW480 cell lysate

Lane 2: Mouse brain tissue lysate

Lane 3: Mouse cerebral cortex tissue lysate

Lane 4: Mouse cerebellum tissue lysate

Lane 5: Mouse spinal cord tissue lysate

Lane 6: Mouse spleen tissue lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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