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Product Information
Description |
LAP2 rabbit polyclonal |
Protein full name |
Lamina-associated polypeptide 2, isoforms alpha/zeta |
Synonyms |
Thymopoietin isoforms alpha/zeta, TP alpha/zeta, Lap2, CMD1T, LAP2, LEMD4, PRO0868, Splenin Thymopentin, thymopoietin, TMPO, TP, TP alpha, TP5, TPRP isoform alpha |
Immunogen |
Recombinant protein corresponding to Mouse LAP2 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Nucleus |
Predicted MW. |
75 kDa |
Observed MW. |
51/75 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
liver, colon |
IHC |
Human, Mouse, Rat | 1: 650-1: 1300 |
|
IF |
Human, Mouse, Rat |
1: 300-1: 1000 |
brain |
Background
The nuclear lamina contains intermediate filament-type proteins called lamins that form a dense network to strengthen and stabilize the nuclear envelope. Lamina-associated polypeptide 2 (LAP2) is also known as thymopoietin. LAP2 is a nuclear envelope protein and contains an amino-terminal region called the LAP2-emerin-MAN1 or LEM motif. LAP2 also contains a unique DNA-binding amino-terminal domain. Alternative splicing produces six isoforms (α, β,γ, ε and δ) of mammalian LAP2 and three isoforms in Xenopus LAP2.
Images
|
Western blot analysis of LAP2 (GB111948) at dilution of 1: 1000 Lane 1: HeLa cell lysate Lane 2: HepG2 cell lysate Lane 3: K562 cell lysate Lane 4: Jurkat cell lysate Lane 5: 293T cell lysate Lane 6: Mouse liver tissue lysate Lane 7: Mouse colon tissue lysate Lane 8: Rat liver tissue lysate |
|
Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using LAP2 (GB111948) at dilution of 1: 600 |
|
Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using LAP2 (GB111948) at dilution of 1: 600 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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