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Product Information
Description |
IL2 Receptor beta/p75 rabbit polyclonal |
Protein full name |
Interleukin-2 receptor subunit beta |
Synonyms |
IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, High affinity IL-2 receptor subunit beta, p70-75, CD122, Il2rb |
Immunogen |
Recombinant protein corresponding to Mouse IL2 Receptor beta/p75 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
61 kDa |
Observed MW. |
70 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain |
Background
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
Images
|
Western blot analysis of IL2 Receptor beta (GB112065) at dilution of 1: 1000 Lane 1: MCF7 cell lysate Lane 2: 293T cell lysate Lane 3: Raji cell lysate Lane 4: HeLa cell lysate Lane 5: HepG2 cell lysate Lane 6: Mouse brain tissue lysate Lane 7: Rat brain tissue lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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