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Product Information
Description |
IL-1RA rabbit polyclonal |
Protein full name |
Interleukin-1 receptor antagonist protein |
Synonyms |
IL-1RN, IL-1ra, IRAP, IL1 inhibitor, DIRA, IL1RA, IL1RN, MVCD4, Type II interleukin 1 receptor antagonist |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse IL-1RA |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
20 kDa |
Observed MW. |
20 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 500-1: 1000 |
pancreas |
Background
IL1RA is a member of the Interleukin 1 cytokine family. This protein inhibits the activities of Interleukin 1, alpha (IL1A) and Interleukin 1, beta (IL1B), and modulates a variety of Interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Images
|
Western blot analysis of IL-1RA (GB112096) at dilution of 1: 1000 Lane 1: Mouse pancreas tissue lysate Lane 2: Rat pancreas tissue lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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