Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling.
Images
Western blot analysis of TNFAIP8L3 (GB112660) at dilution of 1: 1000
Lane 1: MCF7 cell lysate
Lane 2: Jurkat cell lysate
Lane 3: U87 cell lysate
Lane 4: Mouse kidney tissue lysate
Lane 5: Mouse colon tissue lysate
Lane 6: Rat kidney tissue lysate
Lane 7: Rat colon tissue lysate
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer
PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .