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Anti -IL-22RA1 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101687
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

IL-22RA1 rabbit polyclonal

Protein full name

Interleukin-22 receptor subunit alpha-1

Synonyms

IL22RA1, CRF2-9, IL22R, IL22R1, interleukin 22 receptor subunit alpha 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse IL-22RA1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Membrane

Uniprot ID

Q8N6P7, Q80XZ4




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human, Mouse, Rat

1:200-1:400

colon, stomach, lung,

kidney, spleen

IF

Human, Mouse, Rat

1:200-1:400

colon, stomach, lung,

kidney, spleen




Background


Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.




Images



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Immunohistochemistry analysis of paraffin-embedded human colon using IL-22RA1 (GB11302) at dilution of 1: 200

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Immunohistochemistry analysis of paraffin-embedded human stomach using IL-22RA1 (GB11302) at dilution of 1: 200

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Immunohistochemistry analysis of paraffin-embedded mouse lung using IL-22RA1 (GB11302) at dilution of 1: 200




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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