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Product Information
Description |
EMAP II/AIMP1 rabbit polyclonal |
Protein full name |
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 |
Synonyms |
Multisynthase complex auxiliary component p43, EMAP-2, Endothelial monocyte-activating polypeptide II, EMAP-II, Emap2, Scye1, Aimp1, p43, SCYE1 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse EMAP II/AIMP1 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
34 kDa |
Observed MW. |
40 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human |
1: 1000-1: 2000 |
HeLa, 293T, Jurkat, H1299, A549, HepG2, HT-29, MCF7 |
Background
SCYE1(small inducible cytokine subfamily E, member 1) is also named as EMAP2, AIMP1. The human cDNA encodes a 312-amino acid polypeptide that the predicted 34-kDa precursor can be cleaved to produce an active 20-kDa product. SCYE1 is secreted as a result of various stimuli, including TNF-α, heat shock, and hypoxia, and that it acts as a multifunctional cytokine on both endothelial and immune cells. Defects in AIMP1 are the cause of leukodystrophy hypomyelinating type 3 (HLD3). It has 2 isoforms produced by alternative splicing and the protein can exsit as a dimer.
Images
Western blot analysis of AIMP1 (GB113080) at dilution of 1: 2000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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